Severe heart defect likely caused by genetic factors

Hypoplastic Left Heart Syndrome (HLHS), a severe cardiovascular malformation that is difficult to treat and often lethal, is caused primarily by genetic factors, according to a new study by researchers at Cincinnati Children’s Hospital Medical Center. The study – to be published in the Oct. 16 edition of the Journal of the American College of Cardiology – is the first to show the high heritability and likely genetic underpinnings of HLHS and recommend a direction for future research into its cause, development and possible therapeutic strategies.

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<p><a href="http://www.physorg.com/news111240279.html">Severe heart defect likely caused by genetic factors</a></p> <p>Hypoplastic Left Heart Syndrome (HLHS), a severe cardiovascular malformation that is difficult to treat and often lethal, is caused primarily by genetic factors, according to a new study by researchers at Cincinnati Children’s Hospital Medical Center. The study – to be published in the Oct. 16 edition of the <i>Journal of the American College of Cardiology</i> – is the first to show the high heritability and likely genetic underpinnings of HLHS and recommend a direction for future research into its cause, development and possible therapeutic strategies.</p>