Nanowires grown at the National Institute of Standards and Technology (NIST) have a mechanical “quality factor” at least 10 times higher than reported values for other nanoscale devices such as carbon nanotubes, and comparable to that of commercial quartz crystals. Because a high Q factor indicates a capacity for stable vibrations, the nanowires might be used as oscillators in nano-electromechanical systems for future nano-sensors and communications devices.