Although children of alcoholics (COAs) have a greater risk of developing alcohol-use disorders (AUDs), not all COAs will develop AUDs. This study used functional magnetic resonance imaging (fMRI) to examine brain responses to emotional stimuli in adolescent COAs considered “vulnerable” or “resilient” to AUDs. Findings indicate that resilient COAs have greater control over their emotional responses, while vulnerable COAs seem to have difficulties processing emotional stimuli.