Researchers take first step to create cystic fibrosis model using pigs

Cystic fibrosis is the most common genetic disease in Caucasians. The median lifespan for those with the disease is 36 years, and lung disease is the major cause of mortality. For years, scientists have studied cystic fibrosis using mice in which the cystic fibrosis gene was altered. However, mice do not develop lung disease like humans with cystic fibrosis. Now, researchers at the University of Missouri and the University of Iowa have taken the first step in developing a porcine cystic fibrosis model that may more faithfully mimic the disease in humans. The study will be published in the upcoming edition of the Journal of Clinical Investigation.

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<p><a href="http://www.physorg.com/news124097301.html">Researchers take first step to create cystic fibrosis model using pigs</a></p> <p>Cystic fibrosis is the most common genetic disease in Caucasians. The median lifespan for those with the disease is 36 years, and lung disease is the major cause of mortality. For years, scientists have studied cystic fibrosis using mice in which the cystic fibrosis gene was altered. However, mice do not develop lung disease like humans with cystic fibrosis. Now, researchers at the University of Missouri and the University of Iowa have taken the first step in developing a porcine cystic fibrosis model that may more faithfully mimic the disease in humans. The study will be published in the upcoming edition of the <i>Journal of Clinical Investigation</i>.</p>