Specific DNA variations of the serotonin transporter gene can influence drinking intensity

The brain's serotonergic system plays an important role in alcohol preference and consumption. The serotonin transporter gene (SLC6A4), in particular, may regulate a person's propensity for severe drinking. A study of six different single nucleotide polymorphisms – DNA sequence variations – of SLC6A4 has found that they influence drinking intensity among alcohol-dependent (AD) individuals in treatment.

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