Ovarian cancer subtypes are different diseases: Implications for biomarker studies

In a new analysis of tissue biomarkers expressed in ovarian cancer samples, published by PLoS Medicine, David Huntsman and his colleagues from Vancouver General Hospital suggest that substantial differences exist between ovarian cancer subtypes which should be reflected in patient management. Although ovarian cancer is not the most common gynecologic cancer in women, the disease contributes a substantial burden of mortality in part because symptoms are nonspecific and the disease presents late in its course.

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