Scientists find cause of cartilage degeneration in osteoarthritis

The scientists describe their work in this week's Early Edition of the Proceedings of the National Academy of Sciences. In the study, the team shows how the loss of the protein HMGB2, found in the surface layer of joint cartilage, leads to the progressive deterioration of the cartilage that is the hallmark of osteoarthritis.

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<p><a href="http://www.physorg.com/news150991956.html">Scientists find cause of cartilage degeneration in osteoarthritis</a></p> <p>The scientists describe their work in this week's Early Edition of the <i>Proceedings of the National Academy of Sciences</i>. In the study, the team shows how the loss of the protein HMGB2, found in the surface layer of joint cartilage, leads to the progressive deterioration of the cartilage that is the hallmark of osteoarthritis.</p>