Variant form of amyloid beta hinders amyloidogenesis, development of Alzheimer's disease

Alzheimer's disease causes misfolding and aggregation of a protein fragment known as amyloid beta and its deposition as plaques in the brain. This process triggers a cascade of event that leads to neurodegeneration. A new study has found that the deadly transformation of amyloid beta into neurotoxic aggregates can be prevented through its interaction with a variant form of the amyloid beta itself. This opens up new prospects for therapies for the disease.

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<p><a href="http://www.physorg.com/news156088909.html">Variant form of amyloid beta hinders amyloidogenesis, development of Alzheimer's disease</a></p> <p>Alzheimer's disease causes misfolding and aggregation of a protein fragment known as amyloid beta and its deposition as plaques in the brain. This process triggers a cascade of event that leads to neurodegeneration. A new study has found that the deadly transformation of amyloid beta into neurotoxic aggregates can be prevented through its interaction with a variant form of the amyloid beta itself. This opens up new prospects for therapies for the disease.</p>