There are a cluster of metabolic syndrome, that include obesity, high level of fasting plasma glucose, hypertriglyceridemia and hypertension, which is closely associated with the increased morbidity and mortality caused by several of the most common diseases including diabetes, hypertension, cardiovascular diseases, cancer and gallstone disease. However, there are regional and ethic variables in incidence and metabolic risk factors of gallstone disease. No study explores it in china has been reported.