Caffeic acid inhibits colitis in a mouse model -- is a drug-metabolizing gene crucial?

Researchers at Iowa State University have found that increased expression of a form of cytochrome P-450 (CYP4B1) is a key marker of inhibition of colitis in mice by caffeic acid, an anti-inflammatory antioxidant compound widely distributed in foods.

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<p><a href="http://www.physorg.com/news162553970.html">Caffeic acid inhibits colitis in a mouse model -- is a drug-metabolizing gene crucial?</a></p> <p>Researchers at Iowa State University have found that increased expression of a form of cytochrome P-450 (CYP4B1) is a key marker of inhibition of colitis in mice by caffeic acid, an anti-inflammatory antioxidant compound widely distributed in foods.</p>