The immunosuppressive drugs required by organ transplant recipients after surgery can have serious side effects with prolonged use, including infection, heart disease and cancer. In an effort to reduce, or potentially eliminate the need for anti-rejection medications, researchers at Northwestern Memorial Hospital and Northwestern University's Feinberg School of Medicine are investigating the efficacy of a stem cell transplant after organ transplant. The study, which is the first to test the protocol on non-related living donor kidney pairs, involves transplanting stem cells from the kidney donor into the recipient one day following the organ transplant surgery.