2 signals -- from within and out of cell -- specify motor neuron differentiation

Two signals - an external one from retinoic acid and an internal one from the transcription factor Neurogenin2 - cooperate to activate chromatin (the basic material of chromosomes) and help determine that certain nerve progenitor cells become motor neurons, said researchers from Baylor College of Medicine in a report in the current issue of the journal Neuron.

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<p><a href="http://www.physorg.com/news163858356.html">2 signals -- from within and out of cell -- specify motor neuron differentiation</a></p> <p>Two signals - an external one from retinoic acid and an internal one from the transcription factor Neurogenin2 - cooperate to activate chromatin (the basic material of chromosomes) and help determine that certain nerve progenitor cells become motor neurons, said researchers from Baylor College of Medicine in a report in the current issue of the journal <i>Neuron</i>.</p>