Engineering autism: Mice with extra chromosome region show many autistic signs

Mice who inherit a particular chromosomal duplication from their fathers show many behaviors associated with human autism, researchers report in the June 26th issue of the journal Cell, a Cell Press Publication. The duplicated chromosomal region in mice is the equivalent of human chromosome 15q11-13, the most frequent cytogenetic abnormality observed in autism, accounting for some five percent of all cases.

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<p><a href="http://www.physorg.com/news165152905.html">Engineering autism: Mice with extra chromosome region show many autistic signs</a></p> <p>Mice who inherit a particular chromosomal duplication from their fathers show many behaviors associated with human autism, researchers report in the June 26th issue of the journal <i>Cell</i>, a Cell Press Publication. The duplicated chromosomal region in mice is the equivalent of human chromosome 15q11-13, the most frequent cytogenetic abnormality observed in autism, accounting for some five percent of all cases.</p>