Toxic chemicals affect steroid hormones differently in humans and invertebrates

In a study with important consequences for studies on the effects of chemicals on steroid responses in humans, a team of French and American scientists, including Michael E. Baker, PhD, professor in UC San Diego's Department of Medicine, Division of Nephrology-Hypertension, have found that - contrary to earlier assumptions - enzymes used for the synthesis of steroids in insects, snails, octopuses and corals are unrelated to those used in humans.

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