Researchers from Boston University School of Medicine (BUSM), UT Southwestern Medical Center at Dallas, and SEQUENOM, Inc., report the discovery of a genetic variation, that is the strongest known risk factor associated with age-related macular degeneration (AMD). Published in the March 10, 2005, online issue of the journal Science, the study entitled “Complement Factor H Polymorphism and Age-Related Macular Degeneration,” details the discovery of the gene that may account for approximately fifty percent of the cases of AMD in the population.