Researchers Map Circuitry of Yeast Genes Using Technique That Could Be Applied to Humans

Researchers at UCSD have invented a technique that organizes the genetic information contained in the 16 chromosomes of the yeast Saccharomyces cerevisiae into a wiring diagram resembling an electronic circuit board. An analogous diagram of the human genome, when developed, is expected to help in the discovery of the genetic basis of many diseases.
In a paper published in the May issue of Nature Biotechnology, professor Trey Ideker and graduate student Ryan Kelley reported that their new approach allowed them to predict new functions for 343 yeast proteins based on their positions in the new wiring diagram.

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