Forsyth scientists gain greater understanding of how embryos differentiate left from right

Researchers at the Forsyth Institute have discovered a new mechanism responsible for early left/right patterning, the process by which organs locate themselves on the left or right side of the body. The discovery of this novel mechanism, garnered through the study of three different vertebrates (frogs, chickens and zebrafish), marks the first time that a single common mechanism has been identified in left-right patterning in three distinct species. Such a discovery may have far-reaching implications for the understanding of craniofacial development, right-left hand preference, right/left brain dominance and a variety of birth defects in humans.

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