Structure of enzyme offers treatment clues for diabetes, Alzheimer's

Researchers from the University of Chicago and Argonne National Laboratory have deciphered the three-dimensional structure of insulin-degrading enzyme, a promising target for new drugs because it breaks down not only insulin but also the amyloid-beta protein, which has been linked to the cognitive decline of Alzheimer's disease.

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<p><a href="http://www.physorg.com/news79798966.html">Structure of enzyme offers treatment clues for diabetes, Alzheimer's</a></p> <p>Researchers from the University of Chicago and Argonne National Laboratory have deciphered the three-dimensional structure of insulin-degrading enzyme, a promising target for new drugs because it breaks down not only insulin but also the amyloid-beta protein, which has been linked to the cognitive decline of Alzheimer's disease.</p>