Immune responses spread from one protein to another in type 1 diabetes

Type 1 diabetes (T1D) occurs when the immune system inappropriately attacks cells in the pancreas. Although many of the proteins attacked during T1D have been identified, it has not been determined whether immune responses to the individual proteins develop independently or whether a response to one protein then spreads to others. Now, a new study shows that in mice the immune system first attacks a single protein and then expands its attack to other proteins.

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<p><a href="http://www.physorg.com/news84252713.html">Immune responses spread from one protein to another in type 1 diabetes</a></p> <p>Type 1 diabetes (T1D) occurs when the immune system inappropriately attacks cells in the pancreas. Although many of the proteins attacked during T1D have been identified, it has not been determined whether immune responses to the individual proteins develop independently or whether a response to one protein then spreads to others. Now, a new study shows that in mice the immune system first attacks a single protein and then expands its attack to other proteins. </p>