Two Central Mysteries in Genome Inheritance Solved at UCSD

The dance of the chromosomes during cell division, first described in the late 1800s and familiar to all high-school students from movies shown in biology classes, has long fascinated biologists. However, the molecular nature of a key component of cell division, the “chromosome-spindle” connection, which is critical for the inheritance of genetic information as cells divide, has remained elusive.

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