Clock gene plays role in weight gain, study finds

Scientists at the University of Virginia and the Medical College of Wisconsin have discovered that a gene that participates in the regulation of the body’s biological rhythms may also be a major control in regulating metabolism. Their finding shows that mice lacking the gene Nocturnin, which is regulated by the circadian clock in the organs and tissues of mammals, are resistant to weight gain when put on a high fat diet and also are resistant to the accumulation of fat in the liver. This new understanding of weight gain could potentially lead to therapies for inhibiting obesity and for treating its effects on health.

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