High pretreatment PSA velocity predicts worse outcome

The most significant single predictor of aggressive prostate cancer is an elevated rate of increase in prostate specific antigen (PSA) levels, according to a new study. Published in the July 1, 2007 issue of CANCER, a peer-reviewed journal of the [i]American Cancer Society[/i], the study found that a pre-treatment rate of PSA increase, called PSA velocity, of more than 2 ng/ml/year was strongly associated with a high risk of death from prostate cancer.

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