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Medications

Researchers pinpoint issue that could be hampering common chemotherapy drug

Researchers at the University of Toronto's Donnelly Centre for Cellular and Biomolecular Research have found two enzymes that work against the chemotherapy drug gemcitabine, preventing it from effectively treating pancreatic ...

Medications

Metformin during pregnancy impacts offspring brain development, finds study

With the rise in gestational diabetes and metabolic disorders during pregnancy, metformin is also being prescribed more frequently. Although it is known that the oral antidiabetic agent can cross the placental barrier, the ...

Medications

Study eases concern at antipsychotics use in pregnancy

Antipsychotics—a branch of medication designed to treat schizophrenia and bipolar disorder—are important tools for mental health care management. They work by blocking the effect of dopamine, which can help reduce psychotic ...

Medications

Mimicking exercise with a pill

Doctors have long prescribed exercise to improve and protect health. In the future, a pill may offer some of the same benefits as exercise. Now, researchers report on new compounds that appear capable of mimicking the physical ...

Medications

Can over-the-counter cold medicine treat COVID-19?

Research by Cardiff University shows that over-the-counter cold and flu treatments are safe and effective for managing mild COVID-19 symptoms at home and could help alleviate the burden on hospitals during high incidence ...

Medications

Understanding what causes trastuzumab's cardiotoxicity

A new meta-analysis published in OMICS: A Journal of Integrative Biology helps shed light on how changes in mitochondria-related gene expression may cause the cardiotoxicity associated with the cancer therapy trastuzumab.

Medications

Drug design at the atomic level to thwart COVID-19

Although COVID-19 has faded from the headlines, SARS-CoV-2—the coronavirus behind the pandemic—is still rampantly infecting people around the world. Public health officials fear as the virus continues to evolve, it will ...