Scientists' discovery could reduce dependence on animals for vital anticoagulant drug
Heparin, the world's most widely used blood thinner, is used during procedures ranging from kidney dialysis to open heart surgery. Currently, heparin is derived from pig intestines, but scientists at Rensselaer Polytechnic ...
14 hours ago
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Clinical trial shows subcutaneous infusion pump safe, effective for Parkinson's treatment
An international, multisite Phase III trial, co-led by a University of Cincinnati researcher, has found that a Parkinson's disease medication delivered through an infusion pump is safe and effective at reducing symptoms ...
19 hours ago
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Industrial societies losing healthy gut microbes, finds study
Everyone knows that fiber is healthy and an important part of our daily diet. But what is fiber, and why is it healthy? Fiber is cellulose, the stringy stuff that plants are made of. Leaves, stems, roots, stalks, and tree ...
12 hours ago
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Role in mitochondrial metabolism paints more complete picture of MCL-1 function
The life and death of cells are governed by processes that—when disrupted—can lead to cancer. Apoptosis, the process of programmed cell death, is tightly regulated by the B-cell lymphoma-2 (BCL-2) family of proteins. ...
12 hours ago
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Newborn piglets serve as a model for studying influenza
Although prevention and treatment strategies are available for influenza, they are not sufficient for vulnerable populations such as young children and newborns. In a new study published in Virology, a multidisciplinary team ...
17 hours ago
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Deciphering the role of bitter and astringent polyphenols in promoting well-being
Polyphenols are powerful plant metabolites known for their antioxidant properties, offering potential health benefits and protection against various diseases. With over 8,000 identified varieties, these substances are found ...
12 hours ago
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Biden to sign order expanding health research in women
President Joe Biden plans to sign an executive order on Monday that will broaden the scope of medical research in women.
15 hours ago
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A new approach to tissue engineering improves blood vessel formation in rats
Losing a large amount of soft tissue from an injury or cancer may require reconstructive surgery. These surgeries typically rely on a structural framework that holds cells or tissues together made from hydrogels or other ...
Mar 15, 2024
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Sleep-wake rhythm: Fish change our understanding of sleep regulation
Contrary to common belief, not all vertebrates regulate their sleep-wake rhythm in the same way. University of Basel researchers have discovered that some fish—unlike humans—do not need orexin to stay awake. This molecule ...
Mar 14, 2024
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First-in-human trial finds new bladder cancer treatment safe
A first-in-human trial led by The University of Western Australia has found injecting an immunotherapy drug directly into the bladder wall to treat cancer is viable and safe.
Mar 14, 2024
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Ginkgo biloba compounds found to improve cognitive function following stroke
Ginkgo Diterpene Lactone Meglumine (GDLM), a group of organic compounds that derive from the Ginkgo biloba plant, can improve cognitive function in patients who recently experienced an acute ischemic stroke, according to ...
Mar 14, 2024
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Studying use of patients' own reprogrammed cells to attack cancer as alternative to more chemo
A process of taking patients' own cells and reprogramming them to fight cancer has been a last-ditch option for blood cancer patients when nothing else worked, but a new study underway in Aurora is trying to determine whether ...
Mar 14, 2024
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Novel oral hormone therapy shows promising results for prostate cancer treatment with radiation therapy
A study led by Daniel Spratt, M.D., Vincent K. Smith Chair in Radiation Oncology at University Hospitals Seidman Cancer Center demonstrates the safety and efficacy of a novel oral hormone therapy, relugolix, in conjunction ...
Mar 13, 2024
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Assessing the impact of fast-track drug approval programs
Over the past decade, regulatory agencies such as the Federal Drug Administration (FDA) in the United States and the and the European Medicines Agency (EMA) in the European Union have put programs in place to get new drugs ...
Mar 13, 2024
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Vitamin D₂ may help preserve honeymoon phase of type I diabetes
A team of medical researchers and doctors affiliated with several universities and two hospitals in the U.S. reports that administration of vitamin D2 to patients newly diagnosed with diabetes type 1 can prolong the so-called ...
Sperm formation step could hold clues to male contraception
A cross-college collaboration is opening new doors in the study of male infertility by breaking down a key step in sperm formation. Isolating the intricacies of meiotic sex chromosome inactivation (MSCI), will now enable ...
Mar 12, 2024
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Study provides new insights into deadly acute respiratory distress syndrome
Researchers at the University of Minnesota Twin Cities may have discovered a mechanical explanation for instability observed in the lungs in cases of acute respiratory distress syndrome (ARDS), particularly in the aftermath ...
Mar 12, 2024
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Metadata to ensure quality research and animal welfare
A study conducted by a public-private research team, including the University of Lausanne (UNIL), establishes the first minimal metadata set for animal experimentation, a crucial step towards maximizing the sharing and reproducibility ...
Mar 12, 2024
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