Elusive protein protects malaria parasite from heme

Malaria-infected mice cured by 1 dose of new drug Apr 17, 2007 Johns Hopkins University researchers have cured malaria-infected mice with single shots of a new series of potent, long lasting synthetic drugs modeled on an ancient Chinese herbal folk remedy.

Largest synthetic gene ever built offers insights into anti-malarial drug resistance Jun 06, 2007 Researchers at Georgetown University Medical Center say they are moving closer to understanding why the most lethal form of human malaria has become resistant to drug treatment in the past three decades. They have been able ...

A mechanism to explain biological 'cross-talk' between 24-hour body cycle and metabolism Nov 16, 2007 It’s well known that the body’s energy levels cycle on a 24-hour, or circadian, schedule, and that this metabolic process is fueled by oxygen. Now, researchers at the University of Pennsylvania School of Medicine have found ...

Protein protects brain against compound in lead poisoning, liver disease Dec 06, 2007 Scientists have discovered that a protein known as PEPT2 protects the brains of mice from a naturally occurring but potentially toxic compound present in lead poisoning and in a class of liver diseases that can cause serious ...

Genetic pathway critical to disease, aging found Feb 20, 2008 The same chemical reaction that causes iron to rust plays a similarly corrosive role in our bodies. Oxidative stress chips away at healthy cells and is a process, scientists know, that contributes to a host of diseases and ...

Bloodless Worm Sheds Light on Human Blood, Iron Deficiency Apr 16, 2008 Using a lowly bloodless worm, University of Maryland researchers have discovered an important clue to how iron carried in human blood is absorbed and transported into the body. The finding could lead to developing ...

Elusive protein protects malaria parasite from heme Apr 25, 2008 Researchers at the Virginia Bioinformatics Institute (VBI) at Virginia Tech have identified Heme Detoxification Protein (HDP), a unique protein encoded in the malaria genome that represents a potential target for developing ...

Scientists characterize protein structure of environmentally friendly bacteria May 19, 2008 Scientists at the U.S. Department of Energy's Argonne National Laboratory have determined the structure of a key protein domain in a bacterium that could help with bioremediation of uranium-contaminated land ...