New study firmly ties hormone use to breast cancer

December 14, 2008 By MARILYNN MARCHIONE , AP Medical Writer

(AP) -- Taking menopause hormones for five years doubles the risk for breast cancer, according to a new analysis of a big federal study that reveals the most dramatic evidence yet of the dangers of these still-popular pills.



Content from The Associated Press expires 15 days after original publication date. For more information about The Associated Press, please visit www.ap.org .

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  • Keter - Dec 14, 2008
    • Rank: 1 / 5 (1)
    Based on the women I've known, the risk of getting cancer depends not so much on hormones but on genetic predisposition and diet. A woman who is not predisposed to cancer (this can be roughly gauged by their family history and absence of precancerous skin damage from sun exposure) probably isn't at a higher risk, and this group also seems to benefit the most from HRT (increased vitality and remission of symptoms), whereas the at-risk group (determined by the criteria above) seems to have lots of side-effects (bleeding, tenderness in the breasts, etc.).

    Complicating the equation is environmental exposure to chemicals that affect hormones, something that is probably impossible to control or measure. The women I've known who took active steps to limit this chemical exposure generally had fewer menopausal symptoms and were less likely to seek HRT. They also had fewer side-effects from HRT when they did choose it.
  • tkjtkj - Dec 14, 2008
    • Rank: not rated yet
    Based on the women I've known, the risk of getting cancer depends not so much on hormones but on genetic predisposition


    I seriously question your
    credentials. It is appalling
    that any real scientist or
    physician would make the conclusions
    which you do based on such
    outlandishly inappropriate
    personal observations! You talk
    the words of science yet display
    lack of understanding of its
    methodologies.
  • tkjtkj - Dec 14, 2008
    • Rank: not rated yet
    This seems to be a very good study
    and is most welcome! The bad news
    is that its taken soo many years
    for gov. researchers to do such a
    study! This question was 'on the
    table' in the 1970's !!!!!

    Further, one would expect that
    obesity would cause a parallel
    rise in risk, for the same
    hormonal reasons. However, and
    surprisingly, this is true only
    for POST-menapausal women: the
    fact is that obesity (and its
    associated elevations of estrogenic
    hormones) actually seems to
    protect PRE-menapausal women from
    breast cancer. Much more work
    needs to be done! I hope we wont
    have to wait another 40 years to
    sort tHAT out!
  • fleem - Dec 14, 2008
    • Rank: not rated yet
    What's sad is a cursory search of the literature reveals studies showing this decades ago. Check out the late Dr. John Lee. He has some nice links on his site. Also, progesterone cream can help counter the effects of xenoestrogens.
  • E_L_Earnhardt - Dec 14, 2008
    • Rank: 1 / 5 (1)
    Incomplete research indicates a TEMPERATURE rise within cells predates "accelerated mitosis". If hormonal chemicals cause this effect in reproductive organs they may well be causative!

December 14, 2008 all stories

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