Frequent sex and masturbation in 20s and 30s linked to higher prostate cancer risk

January 26, 2009

Men who are very sexually active in their twenties and thirties are more likely to develop prostate cancer, especially if they masturbate frequently, according to a study of more than 800 men published in the January issue of BJU International.

However the UK research team also found that frequent sexual activity in a man's forties appears to have little effect and even small levels of activity in a man's fifties could offer protection from the disease. Most of the differences were attributed to masturbation rather than sexual intercourse.

The study, led by the University of Nottingham, looked at the sexual practices of more than 431 men who had been diagnosed with prostate cancer before the age of 60, together with 409 controls.

Men who took part in the study were asked about all aspects of their sex life from their twenties onwards, including how old they were when they became sexually active, how often they masturbated and had intercourse, how many sexual partners they had had and whether they had had any sexually transmitted diseases.

"We were keen to look at the links between sexual activity and younger men as a lot of prostate cancer studies focus on older men as the disease is more prevalent in men over 50" says lead author Dr Polyxeni Dimitropoulou, who is now at the University of Cambridge.

"Hormones appear to play a key role in prostate cancer and it is very common to treat men with therapy to reduce the hormones thought to stimulate the cancer cells. A man's sex drive is also regulated by his hormone levels, so this study examined the theory that having a high sex drive affects the risk of prostate cancer."

The study participants, who were recruited by their family doctors, were asked to fill in a questionnaire about their sexual habits in each decade of their life since their twenties.

All the men with prostate cancer had been diagnosed in their fifties. Most of the men who took part in the study (97%) were white and the majority were currently married (84%) or widowed, separated or divorced (12%).

A number of interesting points came out of the study:

• 59% of the men in both groups said that they had engaged in sexual activity (intercourse or masturbation) 12 times a month or more in their twenties. This fell steadily as they got older, to 48% in their thirties, 28% in their forties and 13% in their fifties.
• 39% of the cancer group had had six female partners or more, compared with 31% of the control group.
• Men with prostate cancer were more likely to have had a sexually transmitted disease than those without prostate cancer.
• More men with prostate cancer fell into the highest frequency groups in each decade when it came to sexual activity (intercourse and masturbation) than men in the control group. 40% of men in the cancer group fell into the highest frequency category in their twenties (20 or more times a month) compared to 32% in the control group. Similar patterns were observed in the men's thirties and forties. By the fifties it had evened out, with 31% in each group falling into the most frequent category (ten or more times a month).
• Men with prostate cancer were also more likely to masturbate frequently than men in the control group, with the greatest difference in the twenties (34% versus 24%) and thirties (41% versus 31%). The differences were less pronounced in their forties (34% versus 28%) and by the fifties the cancer group was slightly lower (25% versus 26%).

"What makes our study stand out from previous research is that we focused on a younger age group than normal and included both intercourse and masturbation at various stages in the participants' lives" says Dr Dimitropoulou.

"Overall we found a significant association between prostate cancer and sexual activity in a man's twenties and between masturbation and prostate cancer in the twenties and thirties. However there was no significant association between sexual activity and prostate cancer in a man's forties.

"A possible explanation for the protective effect that men in their fifties appear to receive from overall sexual activity, and particularly masturbation, is that the release of accumulated toxins during sexual activity reduces the risk of developing cancer in the prostate area. This theory has, however, not been firmly established and further research is necessary."

Paper: Sexual activity and prostate cancer risk in men diagnosed at a younger age. Dimitropoulou et al. BJU International. 103, pp 178-185. (January 2009). http://www.bjui.org

Source: Wiley


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  • Szkeptik - Jan 26, 2009
    • Rank: 5 / 5 (8)
    This study doesn't really prove what it says it does. There is no evidence that masturbation and sexual activity are directly linked with cancer.

    It might coincide if a higher libido is the cause in which case it can have it's roots in genetic differences and a myriad of hormone levels.
  • Dreadneck - Jan 26, 2009
    • Rank: 2.3 / 5 (6)
    What a load of bollocks. I'll rank this 'study' in the same category as the "You'll go blind!" theory of masturbation. Anything to keep pushing the religious BS that sex and, above all, sexual pleasure is BAD for you. Remember, every time you masturbate Jesus kills a kitten! Think of the poor kitties! LOL
  • Maxims - Jan 26, 2009
    • Rank: 5 / 5 (7)
    The following BBC article claims "Masturbation cuts cancer risk". Both articles can't be true. (Google for that subject if the link below doesn't work.)

    http://news.bbc.c...2021.stm
  • vladik - Jan 26, 2009
    • Rank: 3.7 / 5 (3)
    Apparently, they are trying to solve the demographic problem with some dirty tricks...
  • LuckyBrandon - Jan 26, 2009
    • Rank: 3.7 / 5 (6)
    if it is true, and a high sex drive does lead to prostate cancer, then im completely boned (no pun intended). BUT, at least I'll die happier than the losers who didn't get as much tang :D
  • Crossrip - Jan 26, 2009
    • Rank: 4 / 5 (4)
    I should be dead right now if this study is correct.
  • la7dfa - Jan 26, 2009
    • Rank: 3 / 5 (2)
    Too late to regret now ;)
  • dirk_bruere - Jan 26, 2009
    • Rank: 3.7 / 5 (3)
    Oh no! Now I'm going to get cancer in addition to hairy palms and blindness!
  • DMorse - Jan 26, 2009
    • Rank: 3.8 / 5 (4)
    This study is hogwash.
  • Roj - Jan 26, 2009
    • Rank: 4.8 / 5 (4)
    [quote]..asked to fill in a questionnaire about their sexual habits in each decade[/quote]

    Its common knowledge that surveys & questionnaires are anecdotal, and inaccurately biased for subjective reasons, much less regarded for accuracy of memories several years in the past.

  • fleem - Jan 26, 2009
    • Rank: 1 / 5 (1)
    Guess I need to write a letter to these "researchers" and remind them that higher hormone levels will surely cause a larger, more biochemically active prostate and more emotional stress, as well--both of which will contribute to cancer. While I'm at it I'll point out that running blindfolded through the woods at night with your hands in your pockets might not be a good idea. I'm sure both statements will help those researchers considerably.

  • MorituriMax - Jan 26, 2009
    • Rank: 2.5 / 5 (2)
    All I need to know is, is it going to fall off?
  • MorituriMax - Jan 26, 2009
    • Rank: 3 / 5 (1)
    It reminds me of an old joke.

    Guy goes to the doctor for his annual checkup.

    Doctor brings his results and says, "I've got good news and bad news."

    Guy says, "Well give me the good news first."

    Doctor, "Your sperm count is one."

    Guy, "What?! That's the GOOD NEWS?! What's the BAD news?!"

    Doctor holds his hands out to either side, "It's this Big and it wants out NOW!"
  • p1ll - Jan 26, 2009
    • Rank: 1 / 5 (1)
    i refuse to believe this hooey!!!
  • freethinking - Jan 27, 2009
    • Rank: 3 / 5 (1)
    Headline should say....Men with more partners have higher rates of STD's and have a higher chance of getting Prostate cancer....

    For it to be related to sexual frequencies they would need to find either virgins that masterbated different amounts, or find married men who only had one partner... Hard to do, but if they don't they can not limit other factors.......

    Boy... its difficult to stay serious on this one....
  • x646d63 - Jan 27, 2009
    • Rank: 4 / 5 (1)
    Wow, a lot of people here obviously spent some time with themselves in their 20s and 30s.

    I don't see why it's such a stretch that frequent ejaculation could lead to prostate problems. After all, the prostate is responsible for much of the seminal fluid.

    My guess is that this is a nutritional acid/base imbalance that occurs with frequent ejaculation. Citrate, for example, is found in a higher quantity in the prostate than any other place in the body. It's possible that an imbalance from long-term use could lead to cancer. We have no idea what citrate is for, after all.

  • bmcghie - Jan 27, 2009
    • Rank: 3 / 5 (1)
    Yeah, because citrate isn't oxidized to release energy in The Citric Acid cycle or anything... you know, that process that occurs in every cell containing mitochondria? (And yes, sperm have mitochondria too.)
  • Truth - Jan 27, 2009
    • Rank: 2.3 / 5 (3)
    Very true, Maxims. The article did say that frequent masterbation protects against cancer. And I've read other reports that point out the many benefits of regular heterosexual activity. Makes me wonder why there is such a war against normal, healthy activity. Religious types really need to get a grip on themselves...!

January 26, 2009 all stories

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