Support for adjunctive vitamin C treatment in cancer

March 6, 2009

Serious flaws in a recent study, which concluded that high doses of vitamin C reduce the effectiveness of chemotherapeutic drugs in the treatment of cancer, are revealed in the current issue of Alternative and Complementary Therapies, a journal published by Mary Ann Liebert, Inc.

In the Medical Journal Watch column of the latest issue, Jack Challem, a personal nutrition coach and nutrition author from Tucson, Arizona, and a regular contributor to the Journal, challenges the findings of a study published in Cancer Research (2008;68:8031-8038), in which the authors conclude that vitamin C given to mice or cultured cells treated with common anti-cancer drugs reduces the antitumor effects of the chemotherapeutic agents.

Challem points out two main problems with the study: the oxidized form of vitamin C (dehydroascorbic acid) and not actual vitamin C (ascorbic acid) was used; and in the mouse experiments, the animals were given toxic doses of dehydroascorbic acid, a compound that is not used as a dietary supplement in humans.

"This study and the subsequent headlines [it generated] were a grievous disservice to physicians and patients with cancer," says Challem. He adds that "considerable positive research…has shown striking benefits from high-dose vitamin C (ascorbic acid) in cancer cells and animals—and in actual human beings."

High-dose intravenous vitamin C is a common form of alternative and complementary therapy for patients receiving chemotherapeutic drugs and is believed to help bring about tumor cell death. In addition, it may promote postsurgical healing by enhancing collagen formation, and increase tissue resistance to tumor spread.

Challem suggests that, "The ideal therapeutic approach would be to tailor individual treatment, including IV vitamin C, from a menu of options."

More information: The report is available free online at http://www.liebertpub.com/act

Source: Mary Ann Liebert


print this article email this article download pdf blog this article bookmark this article     Stumble it Digg this share on Facebook retweet share on Reddit add to delicious
Rate this story - 4.3 /5 (6 votes)

Rank Filter

Move the slider to adjust rank threshold, so that you can hide some of the comments.


Display comments: newest first

  • deatopmg - Mar 06, 2009
    • Rank: 2.5 / 5 (2)
    It is obvious that the not-vitamin C, vitamin C study (Cancer Research (2008;68:8031-8038)) was designed, from the beginning by the industrial medical cartel, to fail. The cartel effectively uses the media as their dupes to disseminate the phony, deceptive results and the media goes along with it because of advertising revenue.

    The medical cartel and their servants, the FDA, will do everything w/in their power to limit the availability and hide the effectiveness of ANY treatment that might damage their bottom line (or in the case of ca. 75% of the FDA employees, limit the possibility of going to work in the cartel).
  • gopher65 - Mar 06, 2009
    • Rank: 1 / 5 (1)
    This guy is a nutrition coach (which requires no training). No background in the (real, non-social) sciences, no (real) research papers published (just new-agey magical-thinking garbage in fake journals), no credentials.

    If someone who, you know, ISN'T A QUACK WITH A BOOK DEAL ON THE LINE comes out and bashes this study, I'll listen. Pharmaceutical companies certainly do publish fake studies from time to time for marketing purposes. But this guy doesn't count as such a person.
  • E_L_Earnhardt - Mar 06, 2009
    • Rank: 1 / 5 (2)
    Did you ever notice that "grass" doesn't grow much in the winter! Little to sell here, but if I didn't want rapid growth of organic cells I would consider the refrigerator!

March 6, 2009 all stories

Comments: 3

4.3 /5 (6 votes)
  • Stumble this up

  • Digg this

  • share this

  • hide
  • Related Stories




  • hide
  • Relevant PhysicsForums posts

  • Obsessive Compulsive Disorder
    created Nov 20, 2009
  • West's zone 2 starling resistor respiratory physiology
    created Nov 18, 2009
  • 50-0-50 rule
    created Nov 18, 2009
  • What is the evidence in support of the anti-vaccine movement?
    created Nov 17, 2009
  • More from Physics Forums - Medical Sciences

Other News

Swine flu vaccine effective despite mutations: experts

Medicine & Health / Diseases

created 5 hours ago | popularity 1 / 5 (1) | comments 1

Swine flu vaccines are still effective despite reported cases of mutations in the A(H1N1) virus, health experts in Europe and North America said Saturday.


GOP: Health test recommendations could affect care (AP)

GOP: Health test recommendations could affect care

Medicine & Health / Health

created 16 hours ago | popularity not rated yet | comments 0

(AP) -- Republicans are seizing on this week's recommendations for fewer Pap smears and mammograms to fuel concern about government-rationed medical care - and to try to chip away support by women for President ...


smoking, cigarette

Vaccine being developed to help smokers quit

Medicine & Health / Medications

created Nov 20, 2009 | popularity 4.3 / 5 (8) | comments 10

(PhysOrg.com) -- Glaxo-SmithKline has joined forces with Nabi Pharmaceuticals to produce a vaccine to help smokers give up their addiction permanently.


Study raises concerns about outdoor second-hand smoke

Medicine & Health / Health

created Nov 18, 2009 | popularity 2 / 5 (4) | comments 21

Indoor smoking bans have forced smokers at bars and restaurants onto outdoor patios, but a new University of Georgia study in collaboration with the Centers for Disease Control and Prevention suggests that these outdoor smoking ...


Pilot study relates phthalate exposure to less-masculine play by boys

Medicine & Health / Research

created Nov 16, 2009 | popularity 4.8 / 5 (9) | comments 9

A study of 145 preschool children reports, for the first time, that when the concentrations of two common phthalates in mothers' prenatal urine are elevated their sons are less likely to play with male-typical toys and games, ...