Housewife Remedy for Scurvy Preceded Medical Discovery
March 11, 2009 by Mary Anne Simpson
Orange Juice. Courtesy: USDA
(PhysOrg.com) -- A 100-page handwritten book by Mrs. Ebot Mitchell written in 1707 on household remedies contains among other things a recipe to treat scurvy. The recipe containing extracts from plants, orange juice, white wine or beer preceded the official medical treatment recommended by James Lind, a British naval surgeon in the late 1740's. Unfortunately, even James Lind's research was not implemented by the British Admiralty until late in the 1700's. Mrs. Mitchell's little handbook entitled "Ebot Mitchell Her Book 1707" was discovered in a house in Hasfield, Gloucestershire and is expected to fetch at auction around $831 (600 GBP) at Bonhams in London on March 24.
Scurvy is a disease which is the result of a diet deficient in Vitamin C. Egyptians recorded the symptoms of the disease as far back as 1550 B.C. James Lind, a British naval surgeon began his investigation of scurvy following the catastrophic world-wide sea voyage of Commander George Anson in the early 1740's wherein only 145 out of some 1100 sailors survived due to scurvy. Dr. Lind found that lemon or lime juice was effective in treating scurvy and recommended all seafaring voyages require sailors to imbibe the juice. The order was not officially approved until late in the 1700s by British Admiralty.
According to Professor Kumaravel Rajakumar MD, Department of Pediatrics, University of Pittsburgh School of Medicine, while the numbers declined in incidences of scurvy among British seafaring voyages a new crop of "land scurvy" developed during the 19th century. Individuals who were affected by the Great Potato Famine, and service members of the American Revolution and Crimean Wars, Arctic explorers and the California Gold Rush mining camps developed scurvy. Again, the culprit was a lack of Vitamin C (ascorbic acid) in the diet.
Pediatric scurvy was identified by Francis Glisson in 1650 in co-occurrence with infantile rickets. His observations and report did not surface for another 200-years. By the end of the 19th century, infantile scurvy was recognized in Britain and the United States and was attributed to the practice of heating milk and process foods deficient in Vitamin C. Eventually, infantile scurvy in the United States was nearly eradicated by supplementing heated milk formulas with fruits, vegetables and potatoes.
According to Dr. Rajakumar,"the human body lacks the ability to synthesize and make Vitamin C and therefore depends on exogenous dietary sources to meet Vitamin C needs. Consumption of fruits and vegetables or diets fortified with Vitamin C are essential to avoid ascorbic acid deficiency." The pathologic manifestations of Vitamin C deficiency include impaired collagen synthesis which can be observed in defective dentine formation, hemorrhaging in the gums, and loss of teeth. Hemorrhaging is a key feature and it can occur in any organ.
Today, infantile scurvy and adult scurvy rarely occurs in developed nations. There has been a significant rise in incidences of scurvy in Refugee Camps and it is reported to be in epidemic proportions in this population. Sudden death due to cardiac arrest is reported among adults and children with scurvy.
According to a manuscript specialist, Mrs. Mitchell's recipe to treat and prevent scurvy was "spot on" with the exception of the wine and beer ingredients. Perhaps, Mrs. Mitchell considered Mary Poppin's advice, that 'a spoon full of sugar, makes the medicine go down, in the most delightful way.'
© 2009 PhysOrg.com
-
US struggles to pinpoint cyber attacks: Top official
Mar 10, 2009 |
not rated yet |
0
-
Software testing market resilient despite crisis: report
Mar 11, 2009 |
not rated yet |
0
-
Research supports toxoplasmosis link to schizophrenia
Mar 11, 2009 |
not rated yet |
0
-
Report: Images from Mars lander show liquid water
Mar 11, 2009 |
not rated yet |
0
-
Engineers build first sub-10-nm carbon nanotube transistor
Feb 01, 2012 |
4.9 / 5 (30) |
30
-
Something old, something new: Evolution and the structural divergence of duplicate genes
Jan 31, 2012 |
4.6 / 5 (7) |
1
-
The hidden nanoworld of ice crystals: Revealing the dynamic behavior of quasi-liquid layers
Jan 30, 2012 |
5 / 5 (3) |
1
-
Stock market network reveals investor clustering
Jan 27, 2012 |
3.9 / 5 (23) |
8
-
Of microchemistry and molecules: Electronic microfluidic device synthesizes biocompatible probes
Jan 26, 2012 |
5 / 5 (1) |
0
-
Classical and Quantum Mechanics via Lie algebras
Apr 15, 2011
- More from Physics Forums - Independent Research
More news stories
Researchers develop new method for creating tissue engineering scaffolds
Researchers at Northwestern University have developed a new method for creating scaffolds for tissue engineering applications, providing an alternative that is more flexible and less time-intensive than current technology.
1 hour ago |
5 / 5 (1) |
0
|
Molecular profiling reveals differences between primary and recurrent ovarian cancers
There is a need to analyze tumor specimens at the time of ovarian cancer recurrence, according to a new study published in Molecular Cancer Therapeutics. Researchers used a diagnostic technology called molecular profiling to examine ...
1 hour ago |
not rated yet |
0
|
Health experts, scientists to discuss bird flu studies
The World Health Organization said Friday it will meet next week to determine whether scientists can publish research on a bird flu virus that may be easily passed among humans.
44 minutes ago |
not rated yet |
0
C-sections linked to breathing problems in preterm infants
Research conducted at Yale School of Medicine shows that a cesarean (C-section) delivery, which was thought to be harmless, is associated with breathing problems in preterm babies who are small for gestational age.
1 hour ago |
not rated yet |
0
US issues guidelines to avoid heparin contamination
Four years after US drug-maker Baxter International's blood thinner heparin was contaminated in China, causing dozens of deaths, US regulators on Friday issued draft guidelines for safe production.
Medicine & Health / Medications
24 minutes ago |
not rated yet |
0
Hovering not hard if you're top-heavy, researchers find
Top-heavy structures are more likely to maintain their balance while hovering in the air than are those that bear a lower center of gravity, researchers at New York University's Courant Institute of Mathematical Sciences ...
Grass to gas: Researchers' genome map speeds biofuel development
Researchers at the University of Georgia have taken a major step in the ongoing effort to find sources of cleaner, renewable energy by mapping the genomes of two originator cells of Miscanthus x giganteus, a large perenn ...
Putting the squeeze on planets outside our solar system
(PhysOrg.com) -- Using high-powered lasers, scientists at Lawrence Livermore National Laboratory and collaborators discovered that molten magnesium silicate undergoes a phase change in the liquid state, abruptly ...
Review: Netflix and Hulu's new scripted originals
Within just over a week, Netflix and Hulu are both debuting their first stabs at original scripted programming.
India probes Google over 'forex transactions'
Indian authorities are probing whether online giant Google broke domestic foreign-exchange transactions rules while shifting funds abroad, the Press Trust of India reported on Friday.
Germany freezes signing of disputed Internet pact
Germany on Friday halted the signing of a controversial international accord billed as a way to beat online piracy that has sparked angry protests, saying it needed more time to consider it.
Mar 12, 2009
Rank: not rated yet
Mar 12, 2009
Rank: not rated yet
Mar 12, 2009
Rank: not rated yet