Lessons from the vaccine-autism wars

May 27, 2009

Researchers long ago rejected the theory that vaccines cause autism, yet many parents don't believe them. Can scientists bridge the gap between evidence and doubt?

This week, the open-access journal investigates why the debunked vaccine-autism theory won't go away. Senior science writer/editor Liza Gross talks to medical anthropologists, science historians, vaccine experts, social scientists, and pediatricians to explore the factors keeping the dangerous notion alive—and its proponents so vitriolic.

Pediatrician Paul Offit has made it his mission to set the record straight: vaccines don't cause autism. But he won't go on Larry King Live—where he could reach millions of viewers—or anyplace celebrity anti-vaccine crusaders like Jenny McCarthy appear. ''Every story has a hero, victim, and villain,'' he explains. ''McCarthy is the hero, her child is the victim—and that leaves one role for you.''

When she read that hecklers were issuing death threats to spokespeople who simply reported studies showing that vaccines were safe, anthropologist Sharon Kaufman dropped her life's work on aging to study the theory's grip on public discourse. To Kaufman, a researcher with a keen eye for detecting major cultural shifts, these unsettling events signaled a deeper trend. ''What happens when the facts of bioscience are relayed to the public and there is disbelief, lack of trust?'' Kaufman wondered. ''Where does that lead us?''

Despite overwhelming evidence that vaccines don't cause autism, one in four Americans still think they do. Not surprisingly, the first half of 2008 saw the largest US outbreak of measles—one of the first to reappear after vaccination rates drop—since 2000, when the native disease was declared eliminated. Mumps and have also made a comeback. Last year in Minnesota, five children contracted Hib, the most common cause of in young children before the vaccine was developed in 1993. Three of the children, including a 7-month-old who died, hadn't received Hib vaccines because their parents either refused or delayed vaccination.

Now, more than ten years after unfounded doubts about safety first emerged, scientists and public health officials are still struggling to get the story out. Their task is made far more difficult by the explosion of misinformation on the Internet, talk shows, and high-profile media outlets, by journalists' tendency to cover the issue as a "debate," and, as Kaufman argues, by an erosion of trust in experts.

Information technology has transformed the way trust and knowledge are produced, Kaufman says: ''Scientists have to consider their role in this changed landscape and how to compete with these other sources of knowledge.'' Simply relating the facts of science isn't enough. No matter that the overwhelming weight of evidence shows that vaccines don't cause . When scientists find themselves just one more voice in a sea of ''opinions'' about a complex scientific issue, misinformation takes on a life of its own.

More information: Gross L (2009) A Broken Trust: Lessons from the Vaccine-Autism Wars. PLoS Biol 7(5): e1000114. doi:10.1371/journal.pbio.1000114, http://biology.plo … pbio.1000114

Source: Public Library of Science (news : web)

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Ashy
May 27, 2009

Rank: 3 / 5 (2)
They will say many words but there will be no any double-blind, placebo-controlled study with really independent specialists taking part. It's disfavour, Pharma know what could be shown at this study.
Nik_2213
May 27, 2009

Rank: not rated yet
Check out the measles epidemic in Wales (UK-ish). These are people who did not get their MMR a decade ago. A bunch are now in 'Intensive Care' with dire complications, some may yet die.

By the way, have we heard from the families who did not get MMR vaccine, got autistic kids anyway, and now have *very sick* kids ??

Um, no, because they're too scared of the Autism Evangelists...

And, sadly, girls who did not get Rubella vaccinations are approaching the age when an infection will ravage their reproductive potential: No grand-children via them...

Were I cruel and/or unfeeling, I might mutter, 'Darwin Award By Proxy' or even 'Evolution in action'.

No, it is just so sad...
Scottza
May 27, 2009

Rank: 3 / 5 (1)
The problem here is that a negative can not be proven. It can not prove that there is no connection between vaccines and increased risk of autism without understanding what does cause autism.
Ashy
May 27, 2009

Rank: 3 / 5 (2)
>measles epidemic in Wales

Yes, many wrong prescribed drugs and many strange diagnosis. It's not study, it's medicine fall. With good doctor and no wrong prescriptions measles is light child disease.

>By the way, have we heard from the families who did not get MMR vaccine, got autistic kids anyway, and now have *very sick* kids ??

MMR not the only reason, but it very strong negative factor.

>And, sadly, girls who did not get Rubella vaccinations are approaching the age when an infection will ravage their reproductive potential: No grand-children via them...

It's another vaccinators' myth. I had rubella and chicken pox at childhood, and mumps at adult. Nothing out of the way. I have healthy child and I know several women without MMR who have healthy children too.

By the way, what about reproductive potential vaccinated people? 5th generation of rabbits being vaccinated with small doses of human vaccines (DPT, polio, and MMR, x3) was sterile. Now we raise 3rd generation of vaccinated humans. What did you say about evolution?
Nik_2213
May 27, 2009

Rank: not rated yet
"I had rubella and chicken pox at childhood, and mumps at adult. Nothing out of the way. I have healthy child and I know several women without MMR who have healthy children too."

I am very glad that you and those others were so fortunate and, hopefully, your child has acquired partial immunity from you. Long may it continue !!

A member of our family worked with many profoundly deaf and otherwise damaged children cruelly hurt by those now-preventable diseases. Sadly, she is no longer with us to render her salty opinion...
PPihkala
May 27, 2009

Rank: not rated yet
I agree that negative can not be proven. I think this vaccine-autism -link has it's roots in the timing of vaccinations and detection of autism. I mean that because children do receive their vaccines at certain age that happens to coincide with the age that autism is many times detected, it's human nature to make a connection between those two, because of convenient timing. Of course this timing does not prove any cause and effect -relation, but it's hard to get that message to parents that for some reason make this apparent connection.

I think that we need to find better, earlier ways to detect autism-related development issues at small children, if possible even evaluating those straight after birth. So when we can get early detection, before they receive any vaccinations, then it can be shown that this autism of certain child was present even before any vaccinations.

Whether that can be accomplished by detecting abnormal levels of metabolites ie by lab test and/or by behaviour studies pointing to abnormal reaction to sound and movement, remains to be seen.
murray
May 28, 2009

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Our experience was that our infant daughter had a very strong negative reaction to the MMR in terms of mental development. I was keeping a word chart of new words she said. After the MMR she got a fever for a few days and was out of sorts for about a month and a half. Up until then she had learned about 20 words. After the MMR she did not learn another word for a month and a half. Something happened. I can see where parents who experience this have no confidences in the unqualified assurances of health officials. Especially after hearing their flip flops on dietary advice every year. Indeed, I recall they showed my wife a video on post-partum care at the hospital and the nurse said to ignore various things said because they had by then been proven wrong. My wife asked, "How do you know the rest is good advice?" ...blank stare...
Rank 2.3 /5 (6 votes)
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