Cardiac arrest resuscitation: Passive oxygen flow better than assisted ventilation

August 12, 2009

Arizona researchers have added another piece to the mounting body of evidence that suggests during resuscitation efforts to treat patients in cardiac arrest, "passive ventilation" significantly increases survival rates, compared to the widely practiced "assisted ventilation."

The study, published in an online edition of Annals of Emergency Medicine, compared the numbers of patients who had suffered a outside a hospital setting and were resuscitated in the field by Emergency Medical Services personnel. Rescuers used either bag-valve-mask ventilation, which forces air into the patient's lungs, or facemasks with a continuous flow of oxygen, which work in a similar fashion to those carried on airplanes in case the cabin pressure drops.

Among the 1,019 adult out-of-hospital cardiac arrest patients in the analysis, 459 received passive ventilation and 560 received bag-valve-mask ventilation. Neurologically normal survival after witnessed cardiac arrest with a shockable heart rhythm was higher for the passive oxygen flow method (38.2 percent) than bag-valve-mask ventilation (25.8 percent).

"These results are strikingly similar to earlier observations from Wisconsin, where survival rates went up from 15 percent to 38 percent after paramedics abandoned the official guidelines for the modified protocol that we developed," says Gordon A. Ewy, MD, a co-author of the study and director of the Sarver Heart Center at The University of Arizona College of Medicine. The Sarver Heart Center's Resuscitation Research Group developed a modified protocol for treating out-of-hospital cardiac arrest called Cardiocerebral Resuscitation, as opposed to Cardiopulmonary Resuscitation, which should be reserved for respiratory arrest (such as near-drowning or drug overdose).

Under the new concept, first tested in Wisconsin, EMS personnel no longer intubated the patient for ventilation. Instead, they applied a facemask delivering a continuous, low-pressure flow of oxygen.

"Our findings provide compelling evidence that positive pressure ventilation is not optimal in the initial management of out-of-hospital cardiac arrest," says lead author Bentley Bobrow, MD, emergency physician at Maricopa Medical Center in Phoenix and associate professor of emergency medicine at the UA College of Medicine. "The work from our EMS providers in Arizona further questions the longstanding dogma of tracheal intubation and ventilation for cardiac arrest.

"We are most pleased that while we are helping to advance the science of resuscitation, we are saving more victims of cardiac arrest in Arizona than ever before," adds Dr. Bobrow, who also is the medical director for the Arizona Department of Health Services Bureau of Emergency Medical Services.

"This study reinforces our belief that survival of out-of-hospital cardiac arrest has more to do with circulating the blood through quality and uninterrupted chest compressions than with ," Dr. Ewy adds.

Source: University of Arizona Health Sciences Center

Filter


Move the slider to adjust rank threshold, so that you can hide some of the comments.


Display comments: newest first

dan42day
Aug 13, 2009

Rank: not rated yet
Seems like I read something awhile back that theorized it was the return of oxygen that caused oxygen-deprived brain cells to self-destruct. Some new resuscitation protocol.

Anyone remember that?

Perhaps forced ventilation is too effective at raising oxygen levels quickly.
Rank 5 /5 (2 votes)
Relevant PhysicsForums posts

More news stories

Complex wiring of the nervous system may rely on a just a handful of genes and proteins

Researchers at the Salk Institute have discovered a startling feature of early brain development that helps to explain how complex neuron wiring patterns are programmed using just a handful of critical genes. ...

Medicine & Health / Research

created 2 hours ago | popularity 5 / 5 (4) | comments 0 | with audio podcast

Human cognitive performance suffers following natural disasters, researchers find

Not surprisingly, victims of a natural disaster can experience stress and anxiety, but a new study indicates that it might also cause them to make more errors - some serious - in their daily lives. In their upcoming Human Fa ...

Medicine & Health / Psychology & Psychiatry

created 4 hours ago | popularity 4 / 5 (1) | comments 0

Both maternal and paternal age linked to autism

Older maternal and paternal age are jointly associated with having a child with autism, according to a recently published study led by researchers at The University of Texas Health Science Center at Houston (UTHealth).

Medicine & Health / Psychology & Psychiatry

created 7 hours ago | popularity 5 / 5 (1) | comments 0 | with audio podcast

New understanding of DNA repair could eventually lead to cancer therapy

A research group in the Faculty of Medicine & Dentistry at the University of Alberta is hoping its latest discovery could one day be used to develop new therapies that target certain types of cancers.

Medicine & Health / Cancer

created 6 hours ago | popularity 4.8 / 5 (4) | comments 0 | with audio podcast

Curry spice component may help slow prostate tumor growth

Curcumin, an active component of the Indian curry spice turmeric, may help slow down tumor growth in castration-resistant prostate cancer patients on androgen deprivation therapy (ADT), a study from researchers ...

Medicine & Health / Cancer

created 8 hours ago | popularity 4.6 / 5 (5) | comments 0 | with audio podcast


Google users warned of threat to smartphone wallets

Users of Google smartphone wallets were being warned on Friday that there is a way to crack pass codes intended to thwart thieves from going on illicit shopping sprees.

Anonymous knocks CIA website offline (Update)

The website of the Central Intelligence Agency was inaccessible on Friday after the hacker group Anonymous claimed to have knocked it offline.

NASA sees wide-eyed cyclone Jasmine

Cyclone Jasmine's eye has opened wider on NASA satellite imagery, as it moves through the Southern Pacific Ocean.

NASA sees Giovanna reach cyclone strength, threaten Madagascar

Tropical Storm 12S built up steam and became a cyclone on February 10, 2012 as NASA's Terra satellite passed overhead. Residents of east-central Madagascar should prepare for this cyclone to make landfall ...

Putting the squeeze on planets outside our solar system

(PhysOrg.com) -- Using high-powered lasers, scientists at Lawrence Livermore National Laboratory and collaborators discovered that molten magnesium silicate undergoes a phase change in the liquid state, abruptly ...

The power of estrogen -- male snakes attract other males

A new study has shown that boosting the estrogen levels of male garter snakes causes them to secrete the same pheromones that females use to attract suitors, and turned the males into just about the sexiest ...