Weeding out marijuana: Researchers close in on engineering recognizable, drug-free Cannabis plant
September 15, 2009In a first step toward engineering a drug-free Cannabis plant for hemp fiber and oil, University of Minnesota researchers have identified genes producing tetrahydrocannabinol (THC), the psychoactive substance in marijuana. Studying the genes could also lead to new and better drugs for pain, nausea and other conditions.
The finding is published in the September issue of the Journal of Experimental Botany. Lead author is David Marks, a professor of plant biology in the College of Biological Sciences.
The study revealed that the genes are active in tiny hairs covering the flowers of Cannabis plants. In marijuana, the hairs accumulate high amounts of THC, whereas in hemp the hairs have little. Hemp and marijuana are difficult to distinguish apart from differences in THC.
With the genes identified, finding a way to silence them—and thus produce a drug-free plant — comes a step closer to reality. Another desirable step is to make drug-free plants visually recognizable. Since the hairs can be seen with a magnifying glass, this could be accomplished by engineering a hairless Cannabis plant.
The researchers are currently using the methods of the latest study to identify genes that lead to hair growth in hopes of silencing them.
"We are beginning to understand which genes control hair growth in other plants, and the resources created in our study will allow us to look for similar genes in Cannabis sativa," said Marks.
"Cannabis genetics can contribute to better agriculture, medicine, and drug enforcement," said George Weiblen, an associate professor of plant biology and a co-author of the study.
As with Dobermans and Dachshunds, marijuana and hemp are different breeds of the same species (Cannabis sativa), but marijuana contains much more THC than hemp, which is a source of industrial fiber and nutritious oil.
Hemp was raised for its fiber — which is similar to cotton but more durable — in the United States until legislation outlawed all Cannabis plants because they contain THC. Today, marijuana contains as much as 25 percent THC, whereas hemp plants contain less than 0.3 percent.
Hemp was once a popular crop in the upper Midwest because it tolerates a cool climate and marginal soils that won't support other crops but, after drug legislation, hemp fiber was replaced by plastic and other alternatives. Recent popular demand for hemp products has led some states to consider the economic and environmental benefits of hemp. North Dakota legislation aims to reintroduce it as a crop, and Minnesota is considering similar legislation. At the same time, California and other states permit the medicinal use of marijuana.
"I can't think of a plant so regarded as a menace by some and a miracle by others," says Weiblen, who is one of the few researchers in the United States permitted to study Cannabis genetics. In 2006, Weiblen and colleagues developed a DNA "fingerprinting" technique capable of distinguishing among Cannabis plants in criminal investigations.
Source: University of Minnesota (news : web)



Oh wait, here's the ticket:
You don't see studies showing how we can make alcoholess gin, do you?
Idiotic, nothing less.
This gives a pretty clear picture of how insainly stupid the prohibition is. The plant can't be studied properly because all that cannabis research has done so far is to show how incredibly useful and beneficial this plant is.
There are other potential benefits however. For example in the south west of Western Australia where I am, the removal of so many trees over the last century has caused a shocking rise of salt laden water tables. These areas were called "wheat belt" before but in many spots now pose an enormous challenge. [Fact: a couple of the rivers flowing out of these areas are now saltier than the sea!]
Well NOBODY is going to persist in smoking stuff that tastes like shit and kills flies out of the air around them. But in WA where flies queue up to buzz into your mouth, to harvest a crop without flies? Beauty!