Mayo Clinic tests non-incision, endoscopic ulcer repair

October 14, 2009

Mayo Clinic surgical researchers are reporting a 93 percent success rate in recent animal tests of endoscopic repair of perforated ulcers. The goal is to advance the use of an endoscope -- which allows access to organs through natural openings, such as the mouth -- for a less invasive alternative to laparoscopic techniques (surgery performed through a small incision) or conventional surgery. They will present their findings from recent animal studies today at the American College of Surgeons 95th Clinical Congress in Chicago.

"Laparoscopic surgery for this condition is only 80 percent successful for a variety of reasons," says Juliane Bingener, M.D., senior author on the study. "In our laboratory experiments we were over 90% successful. We also hope to ultimately reduce the risk to the patient overall and reduce postoperative complications."

The process is called natural orifice translumenal endoscopic surgery (NOTES). The goal is to ultimately limit the physiological impact on the patient. While endoscopic repair limits the level of anesthesia used, in the distant future, it may be done without anesthesia, thus limiting one possible procedural side effect.

"Laparoscopy is great, but not all surgeons do it. It's not easy to do. It's technically advanced," says Erica Moran, M.D., Mayo surgeon and researcher. "But it's already been shown that there are many benefits if we can do noninvasive procedures with people who are actually quite ill."

The researchers are seeking regulatory approval to begin a human clinical trial using the technique in the near future. The advantages of NOTES for ulcer repair:

  • No surgical incision
  • Less discomfort for patient than laparoscopy -- 50 percent less air is introduced into the body
  • Shorter recovery time than conventional surgery
  • Provides ulcer-repair option for candidates too ill for conventional surgery
The doctors emphasize that the endoscopic approach may not be appropriate for all cases. Each patient's background symptoms and other medical conditions would need to be considered in determining which approach to use.

Source: Mayo Clinic (news : web)


print this article email this article download pdf blog this article bookmark this article     Stumble it Digg this share on Facebook retweet share on Reddit add to delicious
Rate this story - not rated yet


October 14, 2009 all stories

Comments: 0

not rated yet
  • Stumble this up

  • Digg this

  • share this

  • hide
  • Related Stories

  • Gallbladder removed without external incisions
    created Jul 28, 2008 | popularity not rated yet | comments 0
  • UCSD Medical Center reports United States' first oral appendix removal
    created Mar 17, 2008 | popularity not rated yet | comments 0
  • Gallbladder removal through vagina offers minimally invasive alternative
    created Feb 25, 2009 | popularity not rated yet | comments 0
  • Single-port laparoscopic surgery performed
    created Nov 29, 2007 | popularity not rated yet | comments 0
  • Total Laparoscopic Aortic Surgery Is Feasible, Shows Satisfactory Results
    created Jun 13, 2009 | popularity not rated yet | comments 0



  • hide
  • Relevant PhysicsForums posts

Other News

Implant-based cancer vaccine is first to eliminate tumors in mice

Implant-based cancer vaccine is first to eliminate tumors in mice

Medicine & Health / Cancer

created 16 hours ago | popularity 4.7 / 5 (21) | comments 4

(PhysOrg.com) -- A cancer vaccine carried into the body on a carefully engineered, fingernail-sized implant is the first to successfully eliminate tumors in mammals, scientists report this week in the journal ...


Brain's endocannabinoid signaling pathway kept in check by two enzymes

Medicine & Health / Research

created 14 hours ago | popularity 4 / 5 (4) | comments 1

(PhysOrg.com) -- A research team has shown that blocking the degradation of two naturally occurring cannabinoids in the endocannabinoid signaling pathway of the brain produces marijuana-like behavioral effects in mice, according ...


Scientists find emotion-like behaviors, regulated by dopamine, in fruit flies

Medicine & Health / Neuroscience

created 18 hours ago | popularity 5 / 5 (3) | comments 0

Scientists at the California Institute of Technology have uncovered evidence of a primitive emotion-like behavior in the fruit fly, Drosophila melanogaster. Their findings, which may be relevant to the relationship betwee ...


Study sheds light on brain's fear processing center

Medicine & Health / Research

created 18 hours ago | popularity 5 / 5 (3) | comments 1

Breathing carbon dioxide can trigger panic attacks, but the biological reason for this effect has not been understood. A new study by University of Iowa researchers shows that carbon dioxide increases brain acidity, which ...


Two molecules affecting brain plasticity

Medicine & Health / Neuroscience

created 18 hours ago | popularity 4.8 / 5 (6) | comments 1

(PhysOrg.com) -- You wouldn't want a car with no brakes. It turns out that the developing brain needs them, too.