Curry-cure? Spicing up the effectiveness of a potential disease-fighter

Koji Wada and colleagues note that curcumin is a potent antioxidant found in the spice, turmeric. Clinical trials are checking its safety and effectiveness for colon cancer, psoriasis, and Alzheimer's disease. However, digestive juice in the gastrointestinal tract quickly destroys curcumin so that little actually gets into the blood.

Scientists have known for years that encapsulating insulin and certain other drugs into structures called liposomes can boost absorption. The scientists prepared the liposomes encapsulating curcumin and fed them to laboratory rats. Encapsulating more than quadrupled absorption of curcumin, and also boosted antioxidant levels in the blood. The encapsulating process could be an answer to the problem of increasing curcumin's absorption in the digestive environment of the gastrointestinal tract, they suggest.

More information: "Evaluation of an Oral Carrier System in Rats: Bioavailability and Antioxidant Properties of Liposome-Encapsulated Curcumin", Journal of Agricultural and Food Chemistry, http://pubs.acs.org/stoken/presspac/presspac/full/10.1021/jf9013923

Source: American Chemical Society (news : web)