Paralyzed Belgian patient can't talk after all

February 19, 2010 By MARIA CHENG , AP Medical Writer

(AP) -- It was heralded as a medical miracle. After spending more than two decades in a vegetative state, Rom Houben, a Belgian man in his mid-40s, was suddenly able to communicate, news reports trumpeted last November.

Other experts questioned the method that Houben was apparently using to communicate. The technique is known as "facilitated communication," in which the patient supposedly directs the hand of a speech therapist who typed out his thoughts.

Houben's doctors said it seemed to be genuine. Until now.

Dr. Steven Laureys, a at Liege University Hospital in Belgium, one of Houben's doctors, now acknowledges the technique doesn't work and that while Houben is conscious, he is not communicating.

"We did not have all the facts before," he said Friday. "The story of Rom is about the diagnosis of , not communication."

Houben was injured in a car crash in 1983 when he was 20, and was said to be in a vegetative state, in which a patient is unconscious and there is no evidence of or intentional movement.

Based on bedside tests four years ago, Laureys and his team diagnosed Houben as being conscious, and performed brain scans proving his was more active than other doctors had thought.

Laureys, who was not Houben's treating physician, said the man's family and other doctors brought in a speech therapist to use facilitated communication. "From the start, I did not prescribe this technique," he said. "But it is important not to make judgments. His family and caregivers acted out of love and compassion."

Last November, news of the case first broke in Der Spiegel, a German publication, and The Associated Press and others reported on it as well. Houben's speech therapist claimed she could feel pressure from his hand guiding her on a keyboard. A basic test was performed that ostensibly proved it was Houben who was communicating.

Since then, Laureys has done his own small study of three speech therapists working with minimally conscious patients, including Houben. In two of those cases, including Houben's, the technique failed. Last week, Laureys presented the results at a neuropsychiatry meeting in London.

"To me, it's enough to say this method doesn't work," he said Friday.

Other experts said the technique should never have been used in the first place.

"It's like using an Ouija board," Arthur Caplan, a professor of bioethics at the University of Pennsylvania, said Friday. "It was too good to be true and we shouldn't have believed it."

Last year, Houben's mother claimed her son was writing a book. "Just imagine," Houben ostensibly typed out via his speech therapist. "You hear, see, feel and think but no one can see that."

Tom McMillan, a professor of neuropsychology at the University of Glasgow, said facilitated communication could be used with some patients but should not be used with ones like Houben who had severe brain injuries. "It has an intermediary who can exert control and affect the outcome," he said.

Experts say the larger question of whether people like Houben who have a traumatic brain injury are conscious and alert remains unanswered. Earlier this month, Laureys and others reported finding glimmers of awareness in some apparently vegetative brain-injury patients. (Houben was excluded from that study).

"I hope Rom and his family will stay as an example" of how hard it is to pick up the signs of consciousness, Laureys said. "Even when we know that patients are conscious, we don't know if there is pain or suffering or what they are feeling."

©2010 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

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RubberBaron
Feb 19, 2010

Rank: 5 / 5 (4)
"Houben's doctors said it seemed to be genuine."

They must have been awfully naive. Anyone looking at the video of the so-called 'facilitated communication' could see it was a sham.
Renier
Feb 19, 2010

Rank: 5 / 5 (2)
There is still something called the scientific method. What does "seems" mean?
Husky
Feb 19, 2010

Rank: 1 / 5 (1)
What imho is needed is to monitor a person in this condition realtime in an MRI scanner and provide scripted auditory/visual/sensory stimulation directly to the brain by implanted electrodes. Not only would this give a much more scientific clean picture of a patients internal potential for thought/communication, but also, by building a feedback loop of the measured brain activity in response to electrode stimulation of for instance the visual cortex, the brain activity as result of this exposure could interactively alter the follow up visual stimuli given by monitoring computer software, so the brain not only passively perceives it but gradually learns to steer, amplify and order it as well, as result not only a two way communication channel is established, but perhaps also a step towards (partial) brain damage remediation if the exposed brain feels increasingly tickled by its self induced neural activity and ultimately one hopes to wake up such a person out of deep sleep mode.
RobertKLR
Feb 19, 2010

Rank: 3 / 5 (2)
Science is a set of theories based on approximations, assumptions, and WAGs (Wild Ass Guesses) expressed in precise mathematical terms. It's sad Mr Houben is not getting better.
Husky
Feb 19, 2010

Rank: 1 / 5 (1)
Have there been any documented investigations of trying to rekindle brain activity in persons with this condition by using powerful illicit substances such as amphetamines or hallucinogens such as mushrooms/LSD. I know this would be skating the very edges of several ethical and legal issues, but i believe that (apart from general braindamage that occurs as result of frequent abuse of any of these drugs in high seeking dosages), a short duration exposure to for instance shrooms seriously puts your visual cortex in high gear and LSD is known to tremendously amplify music/sound sensation. Perhaps you could couple this with the previously mentioned method of electrodes/software feedback loop, to kickstart the process in a very dull brain. Note that I merely suggest to contemplate any potential beneficial use of otherwise illigal substances and in a shortterm strictly regulated exposure only, you wouldn't want the therapy become succesfull in way that the patient wakes up as a drug addict.
Caliban
Feb 19, 2010

Rank: 1.7 / 5 (3)
I don't know if any studies have been conducted(officially, at least) using the methodologies you suggest, Husky, but I can imagine that it could be a real brain-scalder to awake from a coma, blind, and subject to psychedelically distorted music. Could be a pleasant sensation, but, on the other hand...
Caliban
Feb 20, 2010

Rank: 2.3 / 5 (3)
There is the research, reported here recently, of those UK scientists using fMRI scanning to determine presence of conscious activity in putatively vegetative individuals. Out of the many tested, they found a couple that were capable of at least limited communication via visualization of specific visual cues, that are processed by distinct, separate areas of the visual(as I recall)cortex. One cue corresponds to an answer of "yes", another, "no".
phlipper
Feb 21, 2010

Rank: 1 / 5 (1)
There is a fellow here in the US that is in a similar state as Mr. Houben. Here, they used a device, with limited sucess, called a teleprompter.
Rank 4.4 /5 (14 votes)
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