New architectures for nano brushes: Bitty structures can be tailored in many shapes

In their latest series of experiments, Duke University engineers have developed a novel approach to synthesize these nano-brushes, which could improve their versatility in the future. These polymer brushes are currently being used in biologic sensors and microscopic devices, such as microcantilevers, and they will play an important role in the future drive to miniaturization, the researchers said.

Nano-brushes are typically made of polymer molecules grown on flat surfaces with strands of the molecules growing up and out from a surface, much like hairs on a brush. Polymers are large man-made molecules ubiquitous in the manufacture of everyday products.

Like microscopic orchard keepers, the Duke scientists have grafted bundles of polymer “limbs” on flat surfaces known as substrates, already covered with brush bristles. In their approach, two dissimilar brushes can be joined and patterned on the micro-scale. Because the “limbs” can be made out of a different substance than the substrate, the scientists believe these nano-structures are able to significantly modify the properties of a given surface.

To make such a nano-brush, scientists add a chemical known as an initiator to the flat surface, which spurs the growth of the strands.

“One of the common ways of growing brushes is much like a dot matrix printer, with an initiator being the ink ‘printed’ onto an inorganic substrate, such as a silicon wafer or a gold surface, which then causes the brush bristles to grow in specified patterns,” said Stefan Zauscher, Alfred M. Hunt Faculty Scholar and associate professor of mechanical engineering and materials science at Duke’s Pratt School of Engineering.

“In our patterning approach we are now also able to initiate polymer brush growth on existing brush substrates and thus obtain patterned block copolymer brushes, just like grafts, on polymeric substrates,” Zauscher said. “The ability to create more intricate brush structures provides the potential for using them in biomedical applications as sensors for the detection of proteins or glucose.”

The results of his team’s experiments were published online in the journal Small. The research is supported by the National Science Foundation.

Zauscher said this new approach could be readily expanded to many other types of polymers, and to make either single or double layers of brushes. These nano-brushes, he said, would have many potential uses, and would open up the possibilities for building more complicated polymer architectures, which are much in demand for current and future technologies.

In recent research, published earlier in the journal Advanced Materials, Zauscher showed that stimulus-responsive nano-brushes resemble and act like sea anemones, which have a multitude of arms reaching up from an attached base. In the same fashion as these sea animals, nano-brushes can be used to capture and release micro-particles as they move across a surface.

“These microstructures have a potential use in microfluidic systems -- such as labs-on-a-chip -- to capture and release particles at predefined locations, much like the sea anemones capture their prey and guide it to their mouths,” Zauscher said.

Other Duke members of the team are Tao Chen and Debby Chang.

Provided by Duke University (news : web)