In the history of inventions, the wheel has been at the origin of major scientific and technological developments: from the creation of astronomical clocks or calculating machines to motor-drawn vehicles and other motor cars. At the molecular scale, the smallest at which a wheel can be created, it represents a major challenge for chemists and physicists. Since the end of the 1990s, chemists in the CEMES have been working on the design of molecular machines equipped with wheels.

Step by step, they have studied this field in depth in collaboration with their colleagues at IBM in Zurich and then at the Free University of Berlin. After observing the random rotation of a flat molecular wheel in 1998, designing and synthesising a mono-molecular wheelbarrow in 2003 and then synthesising a molecular motor in 2005, they last year managed to operate the first molecular rack with a pinion of 1.2 nm in diameter.

Today, these researchers have shown that a molecular wheel mounted on an axle (as short as possible) could rotate. They have succeeded in controlling its direction of rotation. To prepare this nano-mechanical experiment, the CEMES-CNRS chemists designed and synthesised simple molecular machinery made up of an 0.6 nm-long axle-molecule, bound chemically with two triptycene wheels with a diameter of around 0.7 nm (Figure 1). The type of wheel and surface were very carefully chosen. Two notched, "tyre-less" wheels were used because of their maximum adherence to the running surface, an ultraclean copper plate. Its natural roughness presented rows of copper atoms separated by a distance of about 0.3 nm, and about one atom high.

The experiment consisted in delicately placing wheel-axle-wheel molecules on the copper surface and then using scanning tunnelling microscopy (STM) imaging at very low temperature to detect molecules lying in the correct orientation with respect to the rows of atoms on the surface. The STM tip positioned on a wheel made the latter rotate.

By advancing the STM tip, the microscope behaved like a finger to trigger the rotation.

The STM operator followed real-time on his control screen any variations in electrical current passing through the wheel while he was rolling it. Depending on the handling conditions of the molecule, he could choose to turn one wheel and then the other while the molecule advanced, or make the molecule advance without rolling its wheels.

This experiment enabled an approach to understanding at the mono-molecular scale the functionalities that are already known at a macroscopic scale. Without a wheel, some technological advances could not function. For example, separating the seating or technical parts of a vehicle is essential to prevent friction. At a molecular scale, the reasoning and consequences are similar. If the plate of the molecule is not separated from the surface, there is interaction and hence destruction. These results open the way to creating molecular machines. A goal? To be able, one day, to embark in a single molecule the entire machinery of a nano-vehicle: four wheels, a motor, etc.

Citation: Rolling a single molecular wheel at the atomic scale, Leo Grill, Karl Heinz Rieder, Francesca Moresco, Gwenael Rapenne, Sladjana M. Stojkovic, Xavier Bouju, Christian Joachim, Nature Nanotechnology, February 2007, on-line on January 21, 2007.

Source: CNRS