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Scientists develop 'exercise pill'
A U.S. scientist has created an "exercise pill" that activates a gene that tells cells to burn fat, making mice resistant to high-fat diet weight gains.
Salk Institute scientist Ronald Evans and colleagues said by giving ordinary adult mice a synthetic designed to mimic fat, he has been able to chemically switch on PPAR-d, the master regulator gene that controls the ability of cells to burn fat. Even when the mice are not active, turning on the chemical switch activates the same fat-burning process that occurs during exercise.
The resulting shift in energy balance makes the mice resistant to weight gain even on a high fat diet.
Evans, who presented the study Monday in Washington during the Experimental Biology 2007 meeting, said his findings might lead to a new approach to the treatment and prevention of human metabolic syndrome.
Copyright 2007 by United Press International
The resulting shift in energy balance makes the mice resistant to weight gain even on a high fat diet.
Evans, who presented the study Monday in Washington during the Experimental Biology 2007 meeting, said his findings might lead to a new approach to the treatment and prevention of human metabolic syndrome.
Copyright 2007 by United Press International
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