Under magnetic force, nanoparticles may deliver gene therapy
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Transmission electron microscopy image of a magnetic nanoparticle. Credit: The Children's Hospital of Philadelphia
After binding DNA segments to tiny iron-containing spheres called nanoparticles, researchers have used magnetic fields to direct the nanoparticles into arterial muscle cells, where the DNA could have a therapeutic effect. Although the research, done in cell cultures, is in early stages, it may represent a new method for delivering gene therapy to benefit blood vessels damaged by arterial disease.
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