Dominant cholesterol-metabolism ideas challenged by new research

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Aminophospholipid translocase concentrates the phospholipid PS on the inside of the cell. Credit: PSU
Aminophospholipid translocase concentrates the phospholipid PS on the inside of the cell. Credit: PSU

A team of researchers investigating cholesterol and lipid transport has performed experiments that cast serious doubt on the dominant hypothesis of how the body rids its cells of "bad" cholesterol (LDL) and increases "good" cholesterol (HDL). Cholesterol metabolism is an area of intense inquiry because high levels of LDL cholesterol or total cholesterol put about half of all Americans at significant risk of heart disease.


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