Stomach stem cell discovery could bring cancer insights

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In this image of the mouse antral stomach the bright green cell is a gastric progenitor cell. The cell has activated the mouse villin promoter which drives expression of the green fluorescent protein (GFP). Cells that express GPF can be seen easily u ...
In this image of the mouse antral stomach, the bright green cell is a gastric progenitor cell. The cell has activated the mouse villin promoter, which drives expression of the green fluorescent protein (GFP). Cells that express GPF can be seen easily under the microscope and can be isolated by specialized cell sorting machines. This green progenitor cell will divide to give rise to all of the other cells that make up the flask-like cells that make up this portion of the stomach. The ability to regenerate the glands is a stem cell property. Credit: Gumucio Lab, University of Michigan Medical School

Scientists have identified and described stem cells specific to several tissues and organs of the body — key master cells that give rise to the specialized cell types characteristic of that organ. But to date, it hasn’t been possible to pinpoint functioning stem cells in the stomach, either in laboratory animals or people.


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All News summaries for October 04, 2007

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