New picture of HIV-1's protein jacket identifies target for antibody-based vaccine

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A schematic of the HIV-1 surface protein gp41 and the membrane proximal ectodomain region (MPER). Credit: Steve Moskowitz
A schematic of the HIV-1 surface protein gp41 and the membrane proximal ectodomain region (MPER). Credit: Steve Moskowitz

By coaxing the HIV-1 protein to reveal a hidden portion of its protein coat, scientists at Dana-Farber Cancer Institute and Harvard Medical School have provided a newly detailed picture of how protective, or so-called broadly neutralizing, antibodies block HIV-1 infection.


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All News summaries for January 10, 2008

Study challenges routine use of MRI scans to evaluate breast cancer

3 hours ago | User rating: not rated yet
A new study suggests women with newly-diagnosed breast cancer who receive an MRI after their diagnosis face delays in starting treatment and are more likely to receive a mastectomy. The study, presented today at the 2008 ...

Patients will face delays in getting diagnostic scans due to severe shortage of imaging agents

Sep 06, 2008 | User rating: not rated yet
A global shortage of medical isotopes* used in over 80% of routine diagnostic nuclear imaging procedures such as heart imaging, bone scans and some cancer detection procedures, will cause delays and cancellations to diagnostic ...

Parsing the genome of a deadly brain tumor

Sep 06, 2008 | User rating: not rated yet
The most comprehensive to-date genomic analysis of a cancer – the deadly brain tumor glioblastoma multiforme – shows previously unrecognized changes in genes and provides an overall view of the missteps in the pathways that ...

How STDs increase the risk of becoming infected with HIV

Sep 05, 2008 | User rating: not rated yet
Individuals who have a sexually transmitted disease (e.g., genital herpes, gonorrhea, syphilis, and chlamydia) and women with yeast and bacterial vaginal infections have an increased risk of becoming infected with HIV if ...

Review panel criticizes Great Lakes health study

Sep 05, 2008 | User rating: not rated yet
(AP) -- Substandard science has hurt a federal agency's seven-year effort to document possible links between industrial pollution and health problems in the Great Lakes region, an independent review panel said Friday.
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