Newly developed anti-malarial medicine treats toxoplasmosis

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The DHFR enzyme from the parasites that cause malaria (blue) overlaid with the enzyme from the parasites that cause toxoplasmosis (red) with those residues involved in significant changes in the presence of the drug displayed in stick format. In addi ...
The DHFR enzyme from the parasites that cause malaria (blue) overlaid with the enzyme from the parasites that cause toxoplasmosis (red), with those residues involved in significant changes in the presence of the drug displayed in stick format. In addition both enzymes have their surface displayed. For both figures the modelled inhibitor is colored yellow, red, green, blue and cyan for carbon, oxygen, chlorine, nitrogen and fluorine, respectively. Credit: Milhous-Jacobus-McLeod

A new drug that will soon enter clinical trials for treatment of malaria also appears to be 10 times more effective than the key medicine in the current gold-standard treatment for toxoplasmosis, a disease caused by a related parasite that infects nearly one-third of all humans—more than two billion people worldwide.


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