Findings reveal how dengue virus matures, becomes infectious

This composite shows an image of the dengue virus, top left, taken with cryoelectron microscopy, and, to the right of that image are reconstructions of how virus particles mature as they move through their host cells. Purdue biologists have determined why the virus undergoes structural changes as it matures in host cells and how the changes are critical for enabling the virus to infect new host cells. Other elements of the composite show structural details of the virus and a vital component made of two linked proteins called precursor membrane protein and envelope protein. Credit: Purdue University