Cells on path to becoming mature T-cells more flexible than commonly thought

Contrary to the currently accepted model of T-cell development, researchers at the University of Pennsylvania School of Medicine have found that juvenile cells on their way to becoming mature immune cells can develop into either T cells or other blood-cell types versus only being committed to the T-cell path. The findings appear in this week’s issue of Nature, and have implications for better understanding how T-cell leukemias and other disorders arise.