Scientists identify novel way to prevent cardiac fibrosis

In a study that points to a new strategy for preventing or possibly reversing fibrosis – the scarring that can lead to organ and tissue damage – researchers at the University of California, San Diego School of Medicine have determined that a molecule called Epac (Exchange protein activated by cAMP1), plays a key role in integrating the body’s pro- and anti-fibrotic response. The research will be published in the online edition of the Proceedings of the National Academy of Science the week of April 21.