Few studies consider the appropriate measurements for assessing clinical trials in children

Very few studies have asked what the appropriate measurements are for assessing treatments in clinical trials in children, according to a systematic review of paediatric clinical research conducted since 1950. The review by Ian Sinha and colleagues from the University of Liverpool, published in this week’s PLoS Medicine, also shows that few studies have involved parents and none have involved children in the process to select which measurements to use to assess clinical trials.