Engineers create bone that blends into tendons

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A microscopic image of a 10 mm collagen scaffold containing a uniform distribution of skin cells (blue) seeded on top of a 3-D polylysine gradient (green). Credit: Andres GarciaGeorgia Tech
A microscopic image of a 10 mm collagen scaffold containing a uniform distribution of skin cells (blue) seeded on top of a 3-D polylysine gradient (green). Credit: Andres Garcia/Georgia Tech
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Engineers at Georgia Tech have used skin cells to create artificial bones that mimic the ability of natural bone to blend into other tissues such as tendons or ligaments. The artificial bones display a gradual change from bone to softer tissue rather than the sudden shift of previously developed artificial tissue, providing better integration with the body and allowing them to handle weight more successfully. The research appears in the August 26, 2008, edition of the Proceedings of the National Academy of Sciences.


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