Innate immune system targets asthma-linked fungus for destruction

A new study shows that the innate immune system of humans is capable of killing a fungus linked to airway inflammation, chronic rhinosinusitis and bronchial asthma. Researchers at Mayo Clinic and the Virginia Bioinformatics Institute (VBI) have revealed that eosinophils, a particular type of white blood cell, exert a strong immune response against the environmental fungus Alternaria alternata. The groundbreaking findings, which shed light on some of the early events involved in the recognition of A. alternata by the human immune system, were published recently in the Journal of Immunology.