Researchers identify natural tumor suppressor

Researchers from the University of Pennsylvania School of Medicine have identified a key step in the formation – and suppression – of esophageal cancers and perhaps carcinomas of the breast, head, and neck. By studying human tissue samples, they found that Fbx4, a naturally occurring enzyme, plays a key role in stopping production of another protein called Cyclin D1, which is thought to contribute to the early stages of cancer development.